Immune Dysfunction and Cytokine Production in Hemodialysis

Immune dysfunction and cytokine production in hemodialysis. Could they be lessened by vitamin E-coated dialyzer membrane?

BCG modulates neonatal innate immune cytokine production.

Infection causes 0.6 million of the total 2.9 million neonatal deaths every year and devastates the lives of millions more who initially survive; it mercilessly seeks out those weakened by premature delivery and/or low birth weight (LBW), an unfortunate combination too frequently encountered all over the world but particularly so in low-income countries [1]. Reduction of neonatal mortality over...

Cytokine Production in Hymenolepis Nana Infection

Background: Although many experimental studies provide convincing evidence that type II immunity is protective against helminths, recent data in mice demonstrate that Th1 is also impor-tant in some cestodes like Hymenolepis nana. Objective: To identify the role of Th1 and Th2 lymphocytes in immunity against H. nana, the levels of IL-12, IFNγ, IL-5, and IL-13 were de-termined in serum of humans ...

Dissecting innate immune signaling in viral evasion of cytokine production.

In response to a viral infection, the host innate immune response is activated to up-regulate gene expression and production of antiviral cytokines. Conversely, viruses have evolved intricate strategies to evade and exploit host immune signaling for survival and propagation. Viral immune evasion, entailing host defense and viral evasion, provides one of the most fascinating and dynamic interfac...

Cytokine production during in vitro hemodialysis with new and formaldehyde- or renalin-reprocessed cellulose dialyzers.

Critics of reuse have suggested that patients treated with reprocessed dialyzers are exposed to pyrogen trapped from the water or solutions used during the reprocessing cycle, thereby triggering the synthesis and release of proinflammatory cytokines, resulting in cachexia. To test this hypothesis, the production of interleukin (IL)-1 alpha by peripheral blood mononuclear cells (PBMC) during in ...